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Irving Fox Selected Research

Crohn Disease (Crohn's Disease)

1/2018Corrigendum: Exposure-efficacy Relationships for Vedolizumab Induction Therapy in Patients with Ulcerative Colitis or Crohn's Disease.
11/2017A Review of the Clinical Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Vedolizumab.
8/2017Exposure-efficacy Relationships for Vedolizumab Induction Therapy in Patients with Ulcerative Colitis or Crohn's Disease.
1/2017The safety of vedolizumab for ulcerative colitis and Crohn's disease.
11/2016Vedolizumab Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability Following Administration of a Single, Ascending, Intravenous Dose to Healthy Volunteers.
9/2014Effects of vedolizumab induction therapy for patients with Crohn's disease in whom tumor necrosis factor antagonist treatment failed.
11/2013Vedolizumab, a monoclonal antibody to the gut homing α4β7 integrin, does not affect cerebrospinal fluid T-lymphocyte immunophenotype.
8/2013Vedolizumab as induction and maintenance therapy for Crohn's disease.
7/2013Long-term clinical experience with vedolizumab in patients with inflammatory bowel disease.
8/2012Vedolizumab for the treatment of active ulcerative colitis: a randomized controlled phase 2 dose-ranging study.

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Irving Fox Research Topics

Disease

10Crohn Disease (Crohn's Disease)
01/2018 - 08/2012
9Ulcerative Colitis
01/2018 - 08/2012
4Infections
01/2017 - 08/2013
4Neoplasms (Cancer)
01/2017 - 01/2015
2Progressive Multifocal Leukoencephalopathy
01/2018 - 11/2013
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2018 - 07/2013
2Necrosis
08/2017 - 01/2017
1Body Weight (Weight, Body)
11/2017
1Breast Neoplasms (Breast Cancer)
01/2017
1Glioma (Gliomas)
12/2016
1Anus Neoplasms (Anal Cancer)
01/2015
1Intestinal Perforation
01/2015
1Kidney Calculi (Kidney Stone)
01/2015
1Headache (Headaches)
08/2013
1Nasopharyngitis
08/2013
1Abdominal Pain (Pain, Abdominal)
08/2013

Drug/Important Bio-Agent (IBA)

12vedolizumabIBA
01/2018 - 08/2012
4IntegrinsIBA
01/2017 - 08/2013
2AlbuminsIBA
11/2017 - 08/2017
2poly(malic acid)IBA
01/2017 - 12/2016
2Monoclonal AntibodiesIBA
11/2016 - 07/2013
1C-Reactive ProteinIBA
08/2017
1Leukocyte L1 Antigen Complex (Calgranulin)IBA
08/2017
1Antisense OligonucleotidesIBA
01/2017
1Peptides (Polypeptides)IBA
01/2017
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2017
1Analgesics (Analgesic Drugs)IBA
01/2017
1Narcotics (Narcotic Analgesics)IBA
01/2017
1ErbB Receptors (EGF Receptor)IBA
12/2016
1epidermal growth factor receptor VIIIIBA
12/2016
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
12/2016
1Tumor Necrosis Factor InhibitorsIBA
09/2014
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2014
1Natalizumab (Tysabri)FDA Link
11/2013

Therapy/Procedure

6Therapeutics
01/2018 - 08/2013
1Intravenous Infusions
11/2017